Effects of Occupational Exposure on Blood Cells of Radiographers Working in Diagnostic Radiology Department of Khuzestan Province

Document Type: Original Paper

Authors

1 Occupational Hygiene Department, Behbahan Faculty of Medical Sciences, Behbahan, Iran

2 Medical Physics, medical faculty, Jondishapour university, Ahvaz, Iran

3 medical physics, medical faculty, Isfahan University of Medical Sciences, Isfahan, Iran

Abstract

 
Introduction: Because radiology technologists are exposed to protracted low-dose ionizing radiation and considering the possible effects of low-dose radiation on blood factors, we aimed to investigate the effects of occupational exposure on blood factors of radiographers working in radiology departments of Khuzestan Province, Iran.
 
Materials and Methods: This case-control study was conducted in Khuzestan Province, Iran, during 2015. Blood samples were obtained from 95 radiology technologists and 85 matched, nonradiated controls. The participants were chosen using the cluster sampling method.The data were collected by performing complete blood count (CBC) assay with aSysmexcell counter. To analyze the data, t-test and Pearson correlation coefficient were run in SPSS, version 16.
 
Results: T-test demonstrated that the mean values of blood factors were not significantly different between the two groups (P>0.05), and there was no significant difference between the two groups (radiographer and non-radiographer) by gender
 
Conclusion: In this study, occupational exposure did not have any deleterious effects on radiographers’ blood factor levels,but with increasing age and work experience in radiographers,  number of white blood cell decreased.
uction: Because radiologyIntroduction: Because radiology technologists are exposed to protracted low-dose ionizing radiation and considering the possible effects of low-dose radiation on blood factors, we aimed to investigate the effects of occupational exposure on blood factors of radiographers working in radiology departments of Khuzestan Province, Iran.
Materials and Methods: This case-control study was conducted in Khuzestan Province, Iran, during 2015. Blood samples were obtained from 95 radiology technologists and 85 matched, nonradiated controls. The participants were chosen using the cluster sampling method. The data were collected by performing complete blood count (CBC) assay with a Sysmex cell counter. To analyze the data, t-test and Pearson correlation coefficient were run in SPSS, version 16.
Results: T-test demonstrated that the mean values of blood factors were not significantly different between the two groups (P>0.05), and there was no significant difference between the two groups (radiographer and non-radiographer) by gender
Conclusion: In this study, occupational exposure did not have any deleterious effects on radiographers’ blood factor levels, but with increasing age and work experience in radiographers, number of white blood cell decreased. technologists are exposed to protracted low-dose ionizing radiation and considering the possible effects of low-dose radiation on blood factors, we aimed to investigate the effects of occupational exposure on blood factors of radiographers working in radiology departments of Khuzestan Province, Iran.

Materials and Methods: This case-control study was conducted in Khuzestan Province, Iran, during 2015. Blood samples were obtained from 95 radiology technologists and 85 matched, nonradiated controls. The participants were chosen using the cluster sampling method.The data were collected by performing complete blood count (CBC) assay with aSysmexcell counter. To analyze the data, t-test and Pearson correlation coefficient were run in SPSS, version 16.
Results: T-test demonstrated that the mean values of blood factors were not significantly different between the two groups (P>0.05), and there was no significant difference between the two groups (radiographer and non-radiographer) by gender
Conclusion: In this study, occupational exposure did not have any deleterious effects on radiographers’ blood factor levels,but with increasing age and work experience in radiographers,  number of white blood cell decreased.

Keywords

Main Subjects


1.             Baker N, Bromilow L, Costigan J. Exposure to ionising-radiation from x-rays in the intensive therapy unit-St Vincent's Hospital. Australian Critical Care. 1992;5(1):24.

2.             Davoudian Talab A, Badiee Nejad A, Beit Abdollah M, Mahmoudi F, Barafrashtehpour M, Akbari G. Assessment of awareness, performance, and attitudes of radiographers toward radiological protective principles in Khuzestan. Iran J Health Res Community. 2015;1(3):15-23.3.       Tavakoli Mahmood Reza MAZM, Anani Sarab Gholamreza, Hosseini Seyed Mohammad. Evaluation of blood cell count in the radiology staff of Birjand Hospitals in 2011 new care. 2012;9(2):80-6.

4.             Zargan S SS, Emami H, Attarchi M, Yazdanparast T, hamidi H. Comparison of blood cells in radiology workers and non-radiation workers staff of a governmental hospital in Tehran. ioh. 2016;13(4):31-8.

5.             Fang S-P, Tago F, Tanaka T, Simura N, Muto Y, Goto R, et al. Repeated irradiations with γ-rays at a dose of 0.5 Gy may exacerbate asthma. Journal of radiation research. 2005;46(2):151-6.

6.             Schimmöller L, Lanzman R, Dietrich S, Boos J, Heusch P, Miese F, et al. Evaluation of automated attenuation-based tube potential selection in combination with organ-specific dose reduction for contrast-enhanced chest CT examinations. Clinical radiology. 2014;69(7):721-6.

7.             Paolicchi F, Faggioni L, Bastiani L, Molinaro S, Caramella D, Bartolozzi C. Real practice radiation dose and dosimetric impact of radiological staff training in body CT examinations. Insights into imaging. 2013;4(2):239-44.

8.             Brenner DJ, Hall EJ. Computed tomography—an increasing source of radiation exposure. New England Journal of Medicine. 2007;357(22):2277-84.

9.             Barquinero J, Barrios L, Caballin M, Miro R, Ribas M, Subias A, et al. Cytogenetic analysis of lymphocytes from hospital workers occupationally exposed to low levels of ionizing radiation. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 1993;286(2):275-9.

10.          Cengiz M, Gurkaynak M, Vural H, Aksoy N, Cengiz B, Yildiz F, et al. Tissue trace element change after total body irradiation. Nephron Experimental Nephrology. 2003;94(1): 12-6.

11.          Nowak B, Jankowski J. Occupational exposure in operational radiology. International Journal of Occupational Medicine and Environmental Health. 1991;4(2):169-74.

12.          Puthran SS, Sudha K, Rao GM, Shetty BV. Oxidative stress and low dose ionizing radiation. 2009.

13.          Hashim S, Karim M, Bakar K, Sabarudin A, Chin A, Saripan M, et al. Evaluation of organ doses and specific k effective dose of 64-slice CT thorax examination using an adult anthropomorphic phantom. Radiation Physics and Chemistry. 2016;126:14-20.

14.          Protasova O, Maksimov I, Nikiforor A. Altered balance of trace element in blood serum after exposure to low doses of Ionization Radiation. Biol Bull Russ Acad Sci. 2001;28(4):344-9.

15.          Ebrahiminia A S-GD, Karegar A, Farzan A. Relationship between occupational exposure and concentration of some trace elements in radiology and radiotherapy workers J Qazvin Univ Med Sci. 2008;12(3):52-7.

16.          Persson L, editor Effects of low-dose ionizing radiation. Proceedings of the 10th International Congress of the International Radiation Protection Association, May; 2000.

17.          Sayed D, Elwanis MEA, Elhameed SYA, Galal H. Does occupational exposure to low-dose ionizing radiation affect bone marrow thrombopoiesis? International archives of medicine. 2011;4(1):8.

18.          Ward E, Hornung R, Morris J, Rinsky R, Wild D, Halperin W, et al. Risk of low red or white blood cell count related to estimated benzene exposure in a rubberworker cohort (1940–1975). American journal of industrial medicine. 1996;29(3):247-57.

19.          Rozgaj R, Kašuba V, Šentija K, Prlić I. Radiation-induced chromosomal aberrations and haematological alterations in hospital workers. Occupational medicine. 1999;49(6):353-60.

20.          Perkins SL. Examination of the blood and bone marrow. Wintrobe's clinical hematology. 1999:9-35.

21.          Salek Moghaddam A SA, Osati Ashtiani F, Jalali Galousang F. COMPARATIVE EVALUATION OF CELLULAR AND HUMORAL IMMUNITY PARAMETERS IN RADIOGRAPHERS AND NON RADIOGRAPHERS. RJMS. 2004;10(37):727-33.

22.          Forslund T, Welin M-G, Laasonen L, Weber T, Edgren J. Peripheral blood lymphocyte subsets in radiologists exposed to ionizing radiation. Acta Radiologica: Oncology. 1985;24(5):415-7.

23.          Heydarheydari S, Shookoh S, Almasi A, Sohrabi N. Evaluation of the Effects of Ionizing Radiation on Radiation Worker’s Blood Parameters of Kermanshah hospitals. Journal of Clinical Research in Paramedical Sciences Autumn. 2012;1(3).

24.          Kalamzadeh A, Keihani A, Hajati J, Nooraei M, Latifinia A, Zaker F, et al. Total plasma level of antioxidant and immune system function in radiology and nuclear medicine staff. Tehran University Medical Journal TUMS Publications. 2007;65(9):13-9.

25.          Feinendegen LE, Pollycove M, Sondhaus CA. Responses to low doses of ionizing radiation in biological systems. Nonlinearity in biology, toxicology, medicine. 2004;2(3):15401420490507431.

26.          Tucker JD. Low-dose ionizing radiation and chromosome translocations: a review of the major considerations for human biological dosimetry. Mutation Research/Reviews in Mutation Research. 2008;659(3):211-20.

27.          Khedr M. Evaluation the Effect of Low Dose Ionizing Radiation on Radiological Staff. 2017.

28.          Hauck B, Oremek D, Zimmermann R, Ruppel R, Troester B, Eckstein R. Influence of irradiation on in vitro red‐blood‐cell (RBC) storage variables of leucoreduced RBCs in additive solution PAGGS‐M. Vox sanguinis. 2011;101(1):21-7.

29.          Burton R, Ferguson P, Gray M, Hall J, Hayes M, Smart Y. Effects of age, gender, and cigarette smoking on human immunoregulatory T-cell subsets: establishment of normal ranges and comparison with patients with colorectal cancer and multiple sclerosis. Diagnostic immunology. 1983;1(3):216-23.

30.          Tuschl H, Kovac R, Wottawa A. T-lymphocyte subsets in occupationally exposed persons. International journal of radiation biology. 1990;58(4):651-9.

31.          Kusunoki Y, Akiyama M, Kyoizumi S, Bloom ET, Makinodan T. Age-related alteration in the composition of immunocompetent blood cells in atomic bomb survivors. International Journal of Radiation Biology. 1988;53(1):189-98.

32.          Fujiwara S, Akiyama M, Kobuke K, Hakoda M, Kyoizumi S, Olson GB, et al. Analysis of peripheral blood lymphocytes of atomic bomb survivors using monoclonal antibodies. Journal of radiation research. 1986;27(3):255-66.