Analysis of the Attenuation Coefficient of Composite Silicone Rubber and Gliceryn for Soft Tissue Phantom Applications

Document Type : Original Paper

Authors

Department of Physics, Hasanuddin University, Makassar 90245 Indonesia

Abstract

Introduction: Phantom is an object that can be used to investigate the accuracy of radiation dose delivered to patients. Phantom is usually produced from the combination of the silicone rubber as a matrix and glycerin as a filler to form a composite for the replacement of the human soft tissue. The composite is imaged using computed tomography (CT) simulator for the determination of the attenuation coefficient.
Material and Methods: The Phantom in the current study has been synthesized from silicone rubber with and without the addition 10% and 20% of glycerin. The type of silicone rubber in this study was Room Temperature Vulcanized (RTV) 52 with blue catalyst by a ratio of 100:5 (wt%). Samples were scanned using CT simulator to obtain the images and then exported to the Eclipse treatment planning system for analysis. The region of interest (ROI) was at the center of an area of 50×50 pixels to determine the CT number.
Results: The ROI results for the sample without and with the addition of glycerin 10% and 20% resulted in the CT values of 287.4, 280.5, and 225.2 HU, respectively, which were within the ROI range of the human soft tissue. The attenuation coefficients of the 3 samples were 0.239, 0.238±0.001, and 0.233±0.001 cm-1 for no glycerin, glycerin 10%, and glycerin 20%, respectively. The values of the half-value layer were 2.902±0.001, 2.911±0.001, and 2.980± 0.001 cm for phantom with no glycerin, glycerin 10%, and glycerin 20%, respectively.
Conclusion: Phantoms in the current study were indicative of high potentials as an object of research for radiotherapy and educational purposes. Moreover, the composite with glycerin 20% could be the best surrogate of tissue in order to study human liver.

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    1. Murniati R. Nanocomposit of Natural Rubber/Silicone as A Synthetic Muscle with Mechanical Properties Like A Human Muscle. Journal Science Physics. 2018; 10(1): 1-8.
    2. Sidabutar D, Evi S. Comparison of Doses Against Depth Variation and Area of Radiation (Square and Rectangular Forms) on Cobalt-60 Radiotherapy. Youngster Physics Journal. 2014; 3(4): 295- 302.
    3. Ismail HM, Christopher GP, Matthew KS, Marcus H, Cong Z, J.Geoffrey C. Mechanical Behaviour of Tissue Mimicking Breast Phantom Materials, Biomedical Physics & Engineering Express. 2017; 3: 1-17.
    4. Ukhrowiyah N, Novi S, Dyah H, Moh Y. Synthesis and Characterization of Breast-Phantom-Based Gelatine-Glutaraldehyde-TiO2 as a Test Material for The Application of Breast Cancer Diagnosis. Journal of Physics. 2017; 853: 1-10.
    5. Ustbas B, Deniz K, Ayhan B, Mustafa EA, Ozge A. Silicone-Based Composite Materials Simulate Breast Tissue to be used as Ultrasonography Training Phantoms. Ultrasonics. 2018; 1-15.
    6. Fatimah S, Giner M, Suryasatriya T. Homogeneity Analysis of Ultrasonography Image Based on Phantom Silicone Rubber with GLCM. Journal of Physics. 2018; 8(1): 19-28.
    7. Wang Y, Bruce LT, Hongwei Y, Albert JS. Silicone-Based Tissue-Mimicking Phantom for Needle Insertion Simulation. Journal of Medical Devices.2014; 8: 1-7.
    8. Illah MA, Hosta A. Effect of Type of Catalyst on Tensile Strength and Thermal Stability of Polydimethylsiloxane (PDMS) for AISI 1050 Steel Protective Coating. Pomits Engineering Journal. 2013; 2 (1): 41-44.
    9. Cabrelli LC, Felipe WG, Diego RTS, Antonio AOC, Theo ZP.  Acoustic and elastic properties of glycerol in oil-based gel Phantoms. Ultrasound in Medicine & Biology. 2017: 1-9.
    10. Prawitasari J. The Effect of 2% Chlorhexidine Digluconate and Glycerin as a Mixture of Calcium Hydroxide Against the Remaining Calcium Hydroxide in Apical Third Walls of Root Canal Teeth. Journal TeknoSains. 2013; 3(1): 45-50.
    11. Mas’uul AR, Sutanto H.  CT Number Fitness Test In Multi CT Scan Slice In Islamic Hospital Radiology Unit Yogyakarta PDHI. Youngster Physics Journal. 2014; 3(4): 335-340.
    12. Alshipli M, Norlaili AK, Rokiah H, M.W. Marashdeh, Abd Aziz T. Measurement of Attenuation CoeffiCients and CT Numbers of Epoxy Resin and Epoxy-Based Rhizophora Spp Particleboards in Computed Tomography Energy Range. Radiation Physics and Chemistry. 2018; 149: 41–48.
    13. Aufari MA, Robianto S.  Purification of Crude Glycerine Through the Bleaching Process by Using Activated Carbon. Journal of Chemical Engineering. 2013; 2(1): 44-43.
    14. Meilinda T, Eko H, Zaenal A. The Effect of Changing Exposion Factors on Value CT Number, Youngster Physics Journal. 2014; 3(3): 269-278.
    15. Yada N, Hideo O. Validation of Computed Tomography-based Attenuation Correction of Deviation between Theoretical and Actual Values in Four Computed Tomography Scanners. Asia Oceania Journal of Nuclear Medicine & Biology. 2016; 4(2): 81-89.
    16. Artitin C, Suryono, Evi S. Determination of Half Value Layer (HVL) in Digital Computed Radiography Image. Youngster Physics Journal. 2015; 4(1): 55-60.
    17. Setiawan J, Ady P, Risdiyono. Effect of Talc Addition on RTV Silicone Rubber Mold Hardness Value Increasing in Spin Casting Process. Craft and Batik Dynamics. 2017; 34(1): 1-10.
    18. Setiawan J. Research on the Optimal Gas Released Time for Making Rubber Molds with Silicone Rubber RTV. Craft and Batik Dynamics. 2010; 28: 33-36.
    19. King BW, K.A. Landheer, P.C. Johns, X-Ray Coherent Scattering Form Factors of Tissues, Water and Plastics Using Energy Dispersion. Physics in  Medicene and Biology. 2011; 56: 4377–4397.
    20. Boke A. Linear Attenuation Coefficients of Tissues from 1 keV to 150 keV. Radiation Physics Chemistry. 2014; 102: 49-59.
    21. Chirsnia I, Dian M, Heru P, Helfi Y. Conformity Tests of CT-Scan Brand Philips Briliance 6 with The Number 9 Headboard Regulation in 2011. Unand Physics Journal. 2013; 2(2): 120-127.
    22. Yunitasari HD, Evi S, Choirul A. Evaluation of Half Value Layer (HVL) Determination Method Using Multi Purpose Detector (MPD) Barracuda on Mobile X-Ray. Youngster Physics Journal. 2014; 3(2): 113-118.