Enhancing Fricke Xylenol Gel Dosimeter's Response to Radiation with Optimized Preparation Methods.

Document Type : Original Paper

Authors

1 Radiotherapy and Radiation Medicine, Institute of Medical Sciences, Banaras Hindu University.

2 BANARAS HINDU UNIVERSITY

3 Department of Radiotherapy, North Bengal Medical College, Darjeeling, India-734012

4 Radiotherapy and Radiation Medicine, Institute of Medical Sciences, Banaras Hindu University

5 Department of Metallurgical Engineering, Institute of Technology, Banaras Hindu University.

6 Department of Physics, Institute of Technology, Banaras Hindu University

7 Department of Radiotherapy and Radiation Medicine Institute of Medical Sciences Banaras Hindu University VARANASI, Uttar Pradesh, INDIA.

8 RTRM Department, Institute of Medical Sciences, BHU, Varanasi-221005

9 RTRM Department, Institute of Medical Sciences, Banaras Hindu University, Varanasi-221005, INDIA

10 Department of Radiotherapy and Radiation Medicine, Institute of Medical Sciences, Banaras Hindu University.

11 Institute of Medical Science (BHU)Varanasi, UP, India

10.22038/ijmp.2024.74538.2320

Abstract

Purpose



Investigating the radiation dose response of Fricke Xylenol Gel dosimeter under different experimental conditions.



Materials and Methods



Gels were prepared with 300 bloom gelatin, deionized water, sulfuric acid, ferrous ammonium sulfate and xylenol orange dye supplied by Sigma-Aldrich Chemical Company. On preparation, the gel solution was poured into 10ml plastic cuvettes. The gel samples were refrigerated at various temperatures for durations ranging from 1 to 10 days. The gels were subjected to irradiation within a water bath environment utilizing a telecobalt unit (Phoenix, Theratronics) employing parallel opposed beams. Subsequent spectrophotometric evaluations were performed at a wavelength of 585 nm to assess alterations in optical density relative to the absorbed dose. This procedure was repeated across gel formulations prepared under differing pH conditions.



Results



In the case of the optimum pH value of the gel, which was stored for 10 days at 5° C, a linear response was observed up to 10 Gy, although the storage time was long enough than the gels with low (0.3) and high pH (1.3). Auto oxidation rate was determined and was found to be less for non-irradiated gel batches stored at 5° C in relation to the gel samples at room temperature and freezing temperature.



Conclusion



Dose response of the dosimeter is highly dependent of its pH, composition, alkaline residuals and pre-irradiation storing conditions. It may be affected either by the concentration of the gelatin or by increasing the concentration of sulfuric acid. At high pH above 1.3, the dosimeter becomes unstable and is incapable of dose measurements. Furthermore, it shows reduced sensitivity at pH values below 0.3. We observed the optimum pH is 1 at which the dosimeter shows a maximum response. Storing gel samples at 5°C notably reduces Fe2+ to Fe3+ auto-oxidation rate.

Keywords

Main Subjects



Articles in Press, Accepted Manuscript
Available Online from 02 April 2024
  • Receive Date: 22 August 2023
  • Revise Date: 11 March 2024
  • Accept Date: 02 April 2024