@article { author = {Babay Abdollahi, Behnaz and Hamishehkar, Hamed and Ghorbani, Marjan and Naseri, Ali Reza and Farajollahi, Ali Reza}, title = {Core/Shell structured nanoparticles for imaging and therapy}, journal = {Iranian Journal of Medical Physics}, volume = {15}, number = {Special Issue-12th. Iranian Congress of Medical Physics}, pages = {197-197}, year = {2018}, publisher = {Mashhad University of Medical Sciences}, issn = {2345-3672}, eissn = {2345-3672}, doi = {10.22038/ijmp.2018.12814}, abstract = {Introduction: Nanoparticles have several exciting applications in various fields of biomedicine. It has been found that among different classes of nanoparticles core/shell is most promising for field of nano-medical imaging and therapy due to their distinct advantages. The core/shell type nanoparticles can be generally comprising of two nanoparticles one act as a core (inner material) and the second act as a shell (outer layer material). the aim of this study in brief is to explore a historical review of the core/shell nanoparticles in past two decades. Materials and Methods: An organized search of Web of Science, Google Scholar and Scopus was made to select papers with different classes of Core/Shell nanoparticles from the time of introduction to August 2017. The search was limited to English language documents. Titles and abstracts were carefully assessed. Results: Eighty - nine studies were considered as relevant for this review. Of these 64, 18 and 7 studies were classified as inorganic/inorganic, inorganic/organic or organic/inorganic, and organic/organic material core/shell nanoparticles. In general, it is considering that inorganic/inorganic (metal or metal-oxide) core/shell nanoparticles are the most common and important class of all the different types of core/shell nanoparticles but still there are lots of work need to be done in order to verify their applications. Conclusion: It seems that, core/shell nanoparticles have strikingly superior over simple nanoparticles and also the inorganic/inorganic core/shell nanoparticles are extensively studied due to their wide applications in cancer treatment, bio imaging and cell targeting.}, keywords = {Nanoparticle,Biomedical applications,Radiotherapy,Cancer,Radiosensitization}, url = {https://ijmp.mums.ac.ir/article_12814.html}, eprint = {} }