Design and Development of an Indigenous in-house Tissue-Equivalent Female Pelvic Phantom for Radiological Dosimetric Applications

Document Type : Original Paper

Authors

1 DEPARTMENT OF PHYSICS, D.A-V. (P.G.) COLLEGE KANPUR (U.P.)- 208001

2 Department of Physics, D A-V PG College Kanpur

3 Department of Radiotherapy J.K. Cancer Institute Gutaiya, Rawat Pur, Rawatpur Main Road, Kanpur, Uttar Pradesh 208019

4 Department of Radiological Physics, king George Medical University, UP; Lucknow-226003 INDIA

Abstract

Introduction: The present study is aimed to design and develop a tissue-equivalent pelvic phantom, mimicking the Indian female pelvic dimensions by means of locally available and cost-effective tissue substitutes having equivalent radiological properties.
Materials and Methods: For the purpose of the study, the real female pelvic bones were embedded for preparation. Paraffin wax, Aloe-vera powder, purified borax, and sodium benzoate, were used to obtain the proper density and effective atomic number. A hollow three-dimensional outer surface and the internal organs moulds were fabricated using gypsona bandage. The internal organs moulds were filled with semi-solid paraffin wax mixture, stabilized, and then embedded with pelvic bones and internal organs at the right anatomical positions. The surface mould, along with the bones and internal organs, were stabilized in their position in the final form, and verified with computed tomography (CT).
Results: The physical dimensions of the given female pelvic phantom were comparable with the mean dimensions of the Indian female pelvis. Furthermore this tissue-equivalent phantom was radiologically equivalent to the Indian human female pelvis in all respects. The CT numbers of the uterus, bladder, rectum, muscles, fats, bone, and cavities were 39.9, 30.5, 24.7, 34.6, -86.8, 578.6, and -220.9 HU, respectively. Furthermore, the relative electron densities of the muscle, fat and bones were 1.035, 0.913, and 0.779 in the phantom.
Conclusion: The dimensions and physico-radiological properties of the tissue substitutes provided a good inhomogeneous female pelvic phantom differing in dimensions with imported pelvic phantoms. Therefore, this phantom can be used for radiological dosimetric applications.

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  1. References

     

    1. National Cancer Registry Programme. Consolidated report of the population based cancer registries. 1990-1996 (ICMR, New Delhi).
    2. Hayes RL, Brucer M. Compartmentalized phantoms for the standard man, adolescent and child. Int J Appl Radiat Isot. 1960; 9:113-8.
    3. Kinase S, Kimura M, Noguchi H, Yokoyama S. Development of lung and soft tissue subsititutes for photons. Radiat Prot Dosimetry. 2005; 115(1-4):284-8.
    4. American Association for Physicists in Medicine (AAPM). Tissue inhomogeneity correction for megavoltage photon beam AAPM. 2004; Report No. 85.
    5. Winslow J F, Hyer DE, Fisher RF, Tien CJ, Hintenlang DE. Construction of anthropomorphic phantom for use in dosimetry studies. J Appl Clin Med Phys. 2009; 10(3):2986.
    6. White DR. Tissue substitutes in experimental radiation physics. Med. Phys. 1978; 5: 467-479.
    7. White DR. The formation of tissue substitute materials using basic interaction data. Phys Med Biol. 1977; 22(5): 889-99.
    8. White DR, Martin RJ, Darlison R. Epoxy resin based tissue substitute. Br J Radiol. 1977; 50(599): 814-21.
    9. International Commission on Radiation Units and Measurement (ICRU). Tissue substitutes in radiation dosimetry and measurement. 1989; Report No. 44. Bethesda, MD, USA.
    10. International Atomic Energy Agency (IAEA). Absorbed dose determination in external beam radiotherapy: An international code of practice for dosimetry based on standards of absorbed dose to water. 2006; Technical Report No. 398, IAEA, Vienna, Austria.
    11. Followill DS, Evans DR, Cherry C, Molineu A, Fisher G, Hanson WF. et al. Design, development and implementation of the radiological physics center’s pelvis and thorax anthropomorphic quality assurance phantoms. Med Phys. 2007; 34(6).
    12. Nan H, Jinlu S, Shaoxiang Z, Oing H, Li-Wen T, Chengyun G. et al. A CVH-based computational female pelvic phantom for radiation dosimetry simulation. Iran J Radiat Res. 2010, 8(2): 87-91.
    13. Chang SJ, Hung SY, Liu YL, Jiang SH. Construction of Taiwanese Adult Reference Phantom for Internal Dose Evaluation. PloS one. 2016 Sep 12; 11(9):e0162359.
    14. Thomas SJ. Relative electron density calibration of CT scanners for radiotherapy treatment planning. The British Journal of Radiology. 1999, 781-786. 
    15. Singh I, Rawat S, Robert Varte L, Majumdar D. Workstation Related Anthropometric and Body Composition Parameters of Indian Women of Different Geographical Regions. JKIMSU. 2015; Vol.4, No. 1.
    16. Gray H. Anatomy of the Human Body (Bladder). Lea & Febiger; 1878.
    17. Gray H. Anatomy of the Human Body (Uterus). Lea & Febiger; 1878.
    18. Theakston V. The Rectum. Available from:http://techmeanatom.info/abdomen/gi-tract/rectum/.
    19. Winslow J F, Hyer D E, Fisher R F, Tien C J, Hintenlang D E. Construction of anthropomorphic phantom for use in dosimetry studies. Journal of Applied Clinical Medical Physics. 2009; 10(3): 195-204.
    20. Trujillo-Bastidas C D, Garcia-Garduno O A, Larraga-Gutierrez J M, Martinez-Davalos A, Rodriguez-Villafuerte M. Effective atomic number and electron density calibration with a dual-energy CT-technique. AIP Conference Proceeding1747. 2016. Doi: 10.1063/1.4954/29. 
    21. Kanematsu N. Relationship between mass density, electron density, and elemental composition of body tissues for Monte Carlo simulation in radiation treatment planning. Physics in Medicine and Biology. 2016; 61(13): 5037-50.