Development of an Advanced Optical Coherence Tomography System for Radiation Dosimetry

Document Type : Original Paper

Authors

1 Mazanderan University

2 University of Mazandaran

3 Department of Medical Physics Iran University of Medical Sciences, Tehran

Abstract

Introduction: According to the literature, optical coherence tomography (OCT) can be used measure radiation absorbed dose. This study was carried out to design a computed tomography system for the calculation of absorbed dose and optimization of dose delivery in radiotherapy using gel dosimeters.
Material and Methods: An advanced charge-coupled device based OCT system was developed in laboratory with the capability for high resolution three-dimensional (3D) radiation dosimetry using gel dosimeters. The OCT system was compared to magnetic resonance imaging (MRI) as a standard system to investigate its accuracy. Additionally, a number of parameters were checked for assessing the performance of the system.
Results: Developing an advanced OCT system, the calibration curve was drawn for OCT and MRI and the received dose values were compared. The amounts of dose obtained from OCT and MRI were 1.98 and 2 Gy respectively with a relative difference of 2%.
Conclusion: The quality of treatment can be improved using OCT system in radiotherapy dosimetry.

Keywords

Main Subjects


  1. References

     

    1. De Deene Y, De Wagter C, Van Duyse B, Derycke S, De Neve W, Achten E. Three-dimensional dosimetry using polymer gel and magnetic resonance imaging applied to the verification of conformal radiation therapy in head-and-neck cancer. Radiotherapy and Oncology. 1998 Sep 1;48(3):283-91.
    2. Oldham M, Siewerdsen JH, Shetty A, Jaffray DA. High resolution gel‐dosimetry by optical‐CT and MR scanning. Medical physics. 2001 Jul 1;28(7):1436-45.
    3. Doran SJ, Koerkamp KK, Bero MA, Jenneson P, Morton EJ, Gilboy WB. A CCD-based optical CT scanner for high-resolution 3D imaging of radiation dose distributions: equipment specifications, optical simulations and preliminary results. Physics in Medicine & Biology. 2001 Nov 14;46(12):3191.
    4. Gore JC, Ranade M, Maryanski MJ, Schulz RJ. Radiation dose distributions in three dimensions from tomographic optical density scanning of polymer gels: I. Development of an optical scanner. Physics in Medicine & Biology. 1996 Dec;41(12):2695.
    5. Hilts M, Audet C, Duzenli C, Jirasek A. Polymer gel dosimetry using x-ray computedtomography: a feasibility study4. Physics in Medicine & Biology. 2000 Sep 1;45(9):2559.
    6. Maryanski MJ, Zastavker YZ, Gore JC. Radiation dose distributions in three dimensions from tomographic optical density scanning of polymer gels: II. Optical properties of the BANG polymer gel. Physics in Medicine & Biology. 1996 Dec;41(12):2705.
    7. Lopatiuk‐Tirpak O, Langen KM, Meeks SL, Kupelian PA, Zeidan OA, Maryanski MJ. Performance evaluation of an improved optical computed tomography polymer gel dosimeter system for 3D dose verification of static and dynamic phantom deliveries. Medical physics. 2008 Sep 1;35(9):3847-59.
    8. Mather ML, Baldock C. Ultrasound tomography imaging of radiation dose distributions in polymer gel dosimeters: Preliminary study. Medical physics. 2003 Aug 1;30(8):2140-8.
    9. Oldham M. 3D dosimetry by optical-CT scanning. InJournal of Physics: Conference Series 2006 (Vol. 56, No. 1, p. 58). IOP Publishing.
    10. Clift C, Thomas A, Adamovics J, Chang Z, Das I, Oldham M. Toward acquiring comprehensive radiosurgery field commissioning data using the PRESAGE®/optical-CT 3D dosimetry system. Physics in Medicine & Biology. 2010 Feb 4;55(5):1279.
    11. Olding T, Holmes O, Schreiner LJ. Cone beam optical computed tomography for gel dosimetry I: scanner characterization. Physics in Medicine & Biology. 2010 Apr 22;55(10):2819.
    12. Olding T, Schreiner LJ. Cone-beam optical computed tomography for gel dosimetry II: imaging protocols. Physics in Medicine & Biology. 2011 Feb 1;56(5):1259.
    13. Ikeda M, Nakano Y. Spectral luminous-efficiency functions obtained by direct heterochromatic brightness matching for point sources and for 2 and 10 fields. JOSA A. 1986 Dec 1;3(12):2105.