Energy Window Optimization Using Triple Energy Window Scatter Correction Method for In-111 SPECT Imaging: A SIMIND Monte Carlo Study

Document Type : Original Paper

Authors

1 Department of Physics, LPHE, Modeling and Simulations, Faculty of Science, Mohammed V University, Rabat, Morocco

2 Higher Institute of Health Sciences Settat, University HASSAN, Rabat, Morocco

3 Academic Hospital of Udine, Medical Physics Department, Italy

Abstract

Introduction: Detecting scattered photons in the photo peak window degrades the image contrast and quantitative accuracy of single-photon emission computed tomography (SPECT) imaging. This study aimed to determine optimal main- and sub-energy windows for Triple Energy Window (TEW) in In-111.
Material and Methods: We used the simulating medical imaging nuclear detectors (SIMIND) program to simulate the Siemens SYMBIA gamma camera equipped with a medium energy (ME) collimator. We also used the SIMIND Monte Carlo program to generate theIn-111SPECT projection data of the Jaszczak phantom. The phantom consisting of six spheres with different diameters (9.5, 12.7, 19.1, 15.9, 25.4, and 31.8 mm) was used to evaluate the image contrast. Geometric, scatter, and penetration fraction, point spread functions, and contrast curves were drawn and compared.
Results: The results showed that the 171keVphotopeak compared to the 245keVphotopeak yielded the best results with an ME collimator when the TEW scatter correction method was applied. The reason can be the large amount of scatter and penetration from the photo peak and the collimator for the 245keVphotopeak window.
Conclusion: With the TEW scatter correction method, it is better to use a 171keVphotopeak window because of its better spatial resolution and image contrast.

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References

  1. Ogawa K, Harata Y, Ichihara T, Kubo A, Hashimoto S. A practical method for position-dependent Compton-scatter correction in single photon emission CT. IEEE Trans Med Imaging. 1991; 10(3):408-12.
  2. Ogawa K. Simulation study of triple-energy-window scatter correction in combined TI-201. Tc-99m SPECT. Ann Nucl Med. 1994 Nov; 8(4):277-81.
  3. Ogawa K. Simulation study of triple-energy-window scatter correction in combined Tl-201. Tc-99m SPECT. Ann Nucl Med. 1994 Nov; 8(4):277-81.
  4. Takayama T, Ichihara T, Motomura N, Ogawa K. Determination of Energy Window Width and Position for Scintigraphic Imaging Using Different Energy Resolution Detection with the 'Triple Energy Winddw (TEW) Scatter Compensation Method IEEE. Kaku Igaku. 1998 Feb;35(2):51-9.
  5. Dewaraja YK, Li J, Koral K. Quantitative 131I SPECT with triple energy window Compton scatter correction. IEEE Trans Nucl Sc. 1998 Dec; 45(6):3109 –
  6. Lee YS, Kim JS, Kim KM, Lim SM, Kim HJ. Determination of energy windows for the triple energy window scatter correction method in I-131 on a Siemens SYMBIA gamma camera: a GATE simulation study. J Inst. 2015 Jan 15;10:1-8.
  7. Changizi V, Takavar A, Babakhani A, Sohrabi M. Scatter correction for heart SPECT images using TEW method. J Appl Clin Med Phys. 2008 Feb;9(3):136-40.
  8. Asgari A, Ashoor M, Sohrabpour M. Evaluation of various energy windows at different radionuclides for scatter and attenuation correction in nuclear medicine. Ann Nucl Med. 2015;29(4):375-83.
  9. Bong JK, Son HK, Lee JD, Kim HJ. Improved scatter correction for SPECT images: A Monte Carlo study. IEEE Trans Nucl Sc. 2005 Oct; 52(5):1263-70.
  10. Seo Y, Wong KH, Hasegawa BH. Calculation and validation of the use of effective attenuation coefficient for attenuation correction in In-111 SPECT. Med. Phys. 2009; 36: 3040.
  11. Assié K, Dieudonné A, Gardin I, Véra P. A Preliminary Study of Quantitative Protocols in Indium 111 SPECT Using Computational Simulations and Phantoms. IEEE trans nucl sc. 2010; 57:1096-104.
  12. Prior P, Timmins R, Petryk J, Strydhorst J. A modifed TEW approach to scatter correction for In-111and Tc-99m dual-isotope small-animal SPECT Med. Phys. 2016 Oct;43 (10):5503-13.
  13. Ljungberg M. The SIMIND Monte Carlo program home page. 2019. Available from: https://www.msf.lu.se/forskning/the-simindmonte-carlo-program.
  14. Asmi H, Bentayeb F, Bouzekraoui Y and Bonutti F. Evaluation of Acceptance Angle in Iodine-131 Single Photon Emission Computed Tomography Imaging with Monte Carlo Simulation. Indian J Nucl Med. 2019; 34(1):24–
  15. Ferreira T, Rasband W. Image J Program. 2019.Available from:https://imagej.nih.gov/ij/download.html.
Iranian Journal of Medical Physics
Volume 18, Issue 5
September and October 2021
Pages 300-305

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History

  • Receive Date: 25 February 2020
  • Revise Date: 02 August 2020
  • Accept Date: 10 August 2020

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