A Proposed Methodology for Magnetic Resonance Images' Geometrical Distortion Correction Intended To Use For Radiotherapy Planning Using a Large Inhouse Field of View

Document Type : Original Paper


1 Department of medical physics, Faulty of medicine, Mashhad University of Medical Sciences, Mashhad, Iran

2 Mashhad University Of Medical sciences

3 Department of Medical Physics and Radiological Sciences, Sabzevar University of Medical Sciences, Sabzevar, Iran

4 Medical Physics Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

5 Department of Radiotherapy Oncology and Cancer Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

6 Kowsar MRI Center, Emam Reza Hospital, Mashhad, Iran

7 Medical Physics and Radiological Sciences Department, Sabzevar University of Medical Sciences


Introduction: Exquisite soft tissue contrast of magnetic resonance images (MRI) and the new combined radiotherapy system of MR-Linac have been the main impetus for applying MR imaging in radiotherapy. One limitation of MR-based radiotherapy is the geometric distortion of MR images that can generate errors in the contouring and dosimetry stages. This study aimed to evaluate and correct geometric distortion for radiotherapy applications.
Material and Methods: A large field of view (FOV) phantom develop using Perspex sheets and 325 plastic pipes. The quantification and correction of MR images' system-related geometric distortion are conducted for HASTE protocol by MATLAB and 3D slicer software in phantom and patient images. The effect of MRI images geometrical distortion was evaluated for ten patients undergoing body radiotherapy treatment.  CT images were used as a primary dataset to estimate the distortion map.
Results: The phantom investigation results indicate that in radial distances of < 13 cm (or FOVs < 25 cm), the amount of distortion is under 2 mm. Still, at more considerable radial distances, distortion may increase up to about 3.5 cm. MR images of Patients with lateral (LAT) and anterior-posterior (AP) diameters of more than 38 cm and 25 cm respectively, need to be corrected for geometric distortion.  
Conclusion: MR images' geometric precision in large FOVs is not sufficient for MRI only treatment planning of radiotherapy and further corrections are required. The B-spline deformable registration method can correct the MR geometric distortion until an acceptable range of 2 mm for radiotherapy applications.


Main Subjects

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Volume 19, Issue 5
September and October 2022
Pages 305-314
  • Receive Date: 13 February 2021
  • Revise Date: 01 February 2022
  • Accept Date: 08 February 2022
  • First Publish Date: 08 February 2022