Blood of cancerous patients as biomarkers of alpha emitters

Document Type : Original Paper

Authors

1 Department of Physics, College of Science, University of Kerbala, 56001 Kerbala, Iraq

2 Department of Physics, Faculty of Education For Girls, University of Kufa, 54001 Kufa, Iraq

Abstract

Introduction: Radioactive contamination by uranium and its emissions, such as alpha particles, is considered one of the most critical issues affecting the human race and its existence. The high ionization capacity of alpha particles has the most significant impact on the shape and function of living cells, modifying them into malignancies.

Material and Method: The TASLImage solid nuclear trace detector CR-39 was used to measure the effects of alpha emitters in the whole blood samples from 40 cancer patients for five types of cancer (breast, uterus, prostate, kidney, and colon) collected from a government hospital at Karbala/Iraq, and compared with ten healthy samples. Moreover, the research investigated whether smoking and gender variation affect the outcomes.

Results: The radon concentration in whole blood samples from patients and healthy individuals was significantly different (p< 0.05), and it was slightly higher in males with (22.82254+7.38794 Bq/m3). Women with colon cancer had higher blood levels of radon (32.13787+5.79261 Bq/m3) than men with the same malignancy (18.80531+5.63747 Bq/m3), regardless of gender. While the age factor had no noticeable impact, the smoking element had a considerable effect (p< 0.05).

Conclusion: All alpha levels were within the (ICRP) usual ranges. Women with colon cancer had the most significant alpha values. In contrast, men with the same disease had the lowest values despite cancer patients' blood levels being higher than those of the healthy group.

Keywords

Main Subjects

Iranian Journal of Medical Physics

Articles in Press, Accepted Manuscript
Available Online from 10 August 2022

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History

  • Receive Date: 06 April 2022
  • Revise Date: 30 July 2022
  • Accept Date: 10 August 2022
  • First Publish Date: 10 August 2022

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