Iranian Journal of Medical Physics

Iranian Journal of Medical Physics

Dosimetric Characterization of 3D Printed Bolus with Polylactic Acid (PLA) in Breast Cancer External Beam Radiotherapy

Document Type : Original Paper

Authors
Annisa Yuliandari 1
Sri Oktamuliani 1
Harmadi Harmadi 1
Fiqi Diyona 2
1 Departement of Physics, Faculty of Mathematics and Natural Science, Universitas Andalas, Padang, West Sumatra, Indonesia
2 Andalas University Hospital, Padang, West Sumatra, Indonesia
10.22038/ijmp.2023.69705.2231
Abstract
Introduction: In this study, 3-Dimention (3D) polylactic acid (PLA) bolus were characterized as human tissue equivalent and specially designed for use in electron radiotherapy of breast cancer.
Material and Methods: This study uses the main material PLA with variations in the infill percentage when printing, which is  (20, 40, 60, 80, and 100) %. Dosimetric characterization included measuring the value of Relative Electron Density (RED) and measuring the absorbed dose using LINAC 15 MeV, which was tested using a breast mannequin and compared with a commercial bolus at Andalas University Hospital.
Results: The results showed that the 3D bolus made of PLA provided uniformity in terms of thickness so that every part of the body surface covered by the bolus would get an even dose. 3D bolus made of PLA in all variations in the infill percentage had a RED value equivalent to human tissue. They can help ensure that the bolus does not significantly change the radiation dose distribution, achieving optimal treatment outcomes. However, a bolus with an infill percentage of 20% has a RED value closest to the breast RED, which is 0.99 and can absorb radiation of 1.98 Gy more optimally compared to a commercial bolus that can absorb 1.97 Gy from 2 Gy doses given.
Conclusion: The 3D bolus made of PLA can be an effective alternative for treating breast cancer using electron radiotherapy.
Keywords
3D Bolus
Absorbed Dose
Infill Percentage
Polylactic Acid
Relative Electron Density
Subjects
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Iranian Journal of Medical Physics
Volume 21, Issue 3 - Serial Number 3
May and June 2024
Pages 211-216

  • Receive Date 21 December 2022
  • Revise Date 09 April 2023
  • Accept Date 12 April 2023