Change of Hemoglobin Concentration with nano particles can predict breast cancer using near infrared source?

Document Type : Conference Proceedings


Medical radiation sciences research group, Department of Medical Physics, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran


Introduction: Early detection and treatment of breast cancer may be helping to save the lives of patients. Many new techniques have been urban to detect breast cancer. One of them is the use of nano-particles for accuracy and early diagnosis after photo transfer. In this study, rod gold nano particles was used according their ability to change light source transfer intensity.
Material and methods: rod gold nano particles and bloods with 1, 2 and 4 hemoglobin concentrations used to simulate breast cancerous conditions. Nanoparticles with each concentrations of hemoglobin injected into the breast phantom including vessels and transmitted light intensity measured by power meter. Light source was near infrared at 635 wavelengths.
Results: The intensity of the passing lights from normal hemoglobin concentrations was 6.71μw but when measured in the cancerous breast, it declined to 5.59μw and 3.97μw, for twice and four times the concentration of Hb in without nanoparticle condition, respectively.
. When the nanoparticles were blended with hemoglobin concentrations The intensity of the passing lights were determined to be 3.42μw, 2.13μw, and 1.98μw, for, normal, twice and four times the concentration of Hb, respectively.
Conclusions: This study showed that addition of rod gold nano particles to different concentration of hemoglobin provides an effective variation on the near infra red transferring intensity. This study suggests that near-infrared light accompanied by gold nanoparticles has the potential for early breast cancer diagnosis