Development of Artificial Intelligence as a Conversion Tool for Cine Electronic Portal Imaging Device Images to Radiotherapy Dosimetry: Preliminary Study

Document Type : Original Paper

Authors

1 Department of Physics, Faculty of Mathematics and Natural Sciences, Universitas Indonesia

2 Department of Radiotherapy, Cipto Mangunkusumo General Hospital, Jakarta, 10430, Indonesia

Abstract

Introduction: This research is a preliminary study of the development of Artificial Intelligence (AI) as a conversion tool from the pixel value of Cine a-Si 1000 Electronic Portal Imaging Device (EPID) images to dose. It also investigates the relationship between the Monitor Unit (MU), dose rate, number of frames, and beam profile to facilitate further mathematical correction that must be added to create accurate dosimetry by Cine EPID images.

Material and Methods: Homogeneous and inhomogeneous phantom was irradiated in a Linear Accelerator ( Linac) 6 MV with different techniques, field size, and phantom thickness. The Cine a-Si 1000 EPID images were taken and compared to dose distribution data derived from the Eclipse treatment planning system (TPS) at Source Axis Distance 100 cm or isocenter field. The AI model training process begins with the augmentation of EPID and TPS images from homogeneous phantom so that 1152 images are obtained. These images are then split randomly into training and testing data 7:3, and validation is done using gamma index 3%/3mm.

Results: An AI model based on Convolutional Neural Network (CNN) with 6 layers has been successfully created that can convert EPID pixel values into dose distribution without any mathematical correction. The best results from validation with a gamma index of 3%/3mm compared to TPS calculations reached 92.40% ±28.14%.

Conclusions: An AI model has been successfully created that can convert EPID pixel values into dose distribution but need improvement by considering the characteristics contained in the EPID image and the number of datasets.

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Articles in Press, Accepted Manuscript
Available Online from 18 February 2022
  • Receive Date: 11 October 2021
  • Revise Date: 13 February 2022
  • Accept Date: 18 February 2022
  • First Publish Date: 18 February 2022